400 South Australian Avenue, Suite 800

West Palm Beach, Florida 33401

(561) 855-1626


May 11, 2023




Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549


  Re: Rennova Health, Inc.
    Registration Statement on Form S-1
    File No. 333-269077


Ladies and Gentlemen:


Pursuant to Rule 461 under the Securities Act of 1933, as amended, Rennova Health, Inc. hereby respectfully requests that the effective date of the above-referenced Registration Statement on Form S-1 be accelerated to 5:00 p.m., Eastern Time, on Friday, May 12, 2023, or as soon thereafter as is practicable.


Thank you for your courtesy and cooperation.




Rennova Health, Inc.


/s/ Seamus Lagan  
Seamus Lagan  
President and Chief Executive Officer  


cc:   Benjamin Richie (Securities and Exchange Commission)