Annual report pursuant to Section 13 and 15(d)

Schedule of Warrants Activity (Details)

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Schedule of Warrants Activity (Details) - Warrant [Member] - $ / shares
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Accumulated Other Comprehensive Income (Loss) [Line Items]    
Number of Shares of Common Stock Issuable for Warrants, Beginning Balance 467 6
Weighted average exercise price, Beginning Balance $ 195,607 $ 14,400,422
Increase in number of shares of common stock issuable under warrants during the period as a result of down round provisions 54,798,363 462
Number of Shares of Common Stock Issuable for Warrants,expiration of warrants (522,922) (1)
Weighted average exercise price expiration of warrants $ (27.11) $ (3,150)
Number of Shares of Common Stock Issuable for Warrants, issuance of warrants 4,750  
Weighted average exercise price issuance of warrants $ 70.00  
Number of Shares of Common Stock Issuable for Warrants, Ending Balance 54,280,658 467
Weighted average exercise price, Ending Balance $ 1.43 $ 195,607